The Metropolitan Police have reported that a house fire in east London has resulted in the death of a third child.
Just before 8:00 PM BST on Saturday, a terraced property on Napier Road in East Ham caught fire on the ground and first level.
On Saturday morning, one youngster was pronounced dead at the scene of the fire, while another child passed away later that evening.
The mayor of Newham, Rokhsana Fiaz, added: "Three children have now died from a family, and there really are no words to express how as a community we are reeling from the shock and horror of what a house fire can do."
All six people believed to be members of the same family lived in the house and were inside at the time.
Two others remain in hospital while a third has been discharged and is receiving treatment as an outpatient, the force.
Police also said there was no evidence of suspicious circumstances.
A joint investigation by the police and London Fire Brigade (LFB) is under way into the cause of the fire.
Half of the first floor and ground floor of a terraced house were damaged and the blaze was under control by just after 09:00, the fire service added.
LFB Assistant Commissioner Patrick Goulbourne said: "This is a terribly sad incident and the thoughts of all of us at London Fire Brigade are with the family, friends and all those affected at this difficult time."
In a statement posted on Monday evening, Ms Fiaz added that "the family was part of a tight-knit community which is now grieving".
Cheerag Jetha told BBC London on Monday he had lived next door to the family for 10 years and they were "really good neighbours" and a "really nice family".
"At around 08:25 I noticed smoke coming through my window," he said.
"I looked out - I could smell smoke... smoke from my neighbour's back garden, maybe the conservatory area."