In order to start the process of the United States' withdrawal from the World Health Organization (WHO), US President Donald Trump has issued an executive order.

"Oooh, that's a big one," the newly inaugurated US president commented upon returning to the White House and approving the document.

On his first day in office, he signed scores of executive acts, including this one. Trump has now ordered the US to leave the WHO for the second time.

Trump was critical of how the international body handled Covid-19 and began the process of pulling out from the Geneva-based institution during the pandemic. President Joe Biden later reversed that decision.

Carrying out this executive action on day one makes it more likely the US will formally leave the global agency.

"They wanted us back so badly so we'll see what happens," Trump said in the Oval Office, referring to the WHO, perhaps hinting the US might return eventually.

The order said the US was withdrawing "due to the organization's mishandling of the Covid-19 pandemic that arose out of Wuhan, China, and other global health crises, its failure to adopt urgently needed reforms, and its inability to demonstrate independence from the inappropriate political influence of WHO member states".

The executive order also said the withdrawal was the result of "unfairly onerous payments" the US made to the WHO, which is part of the United Nations.

When Trump was still in office the first time around he was critical of the organization for being too "China-centric" in its tackling of the Covid-19 pandemic.

Trump accused the WHO of being biased towards China in how it issued guidance during the outbreak.

Under the Biden administration the US continued to be the largest funder of the WHO and in 2023 it contributed almost one-fifth of the agency's budget.

The organization's annual budget is $6.8 billion (£5.5 billion).

Public health experts have been critical of Trump's decision to leave the WHO, warning there could be consequences for Americans' health.

Some have suggested the move could reverse progress made on fighting infectious diseases such as malaria, tuberculosis and Hiv & Aids.

Ashish Jha, who formerly worked as Covid-19 response co-ordinator under President Biden, previously warned leaving would "harm not only the health of people around the world, but also US leadership and scientific prowess".

"It's a cataclysmic presidential decision. Withdrawal is a grievous wound to world health, but a still deeper wound to the US," Lawrence Gostin, a global public health expert and Georgetown University professor said.